PharmaInsight - Page 2
GLP-1 Agonists and Weight Loss: How These Diabetes Drugs Are Changing Obesity Treatment
GLP-1 agonists like Ozempic and Wegovy were designed for diabetes but now lead the weight loss revolution. Learn how they work, who benefits most, their surprising brain and heart perks, and the real costs and side effects.
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Statin-Induced Muscle Pain: Understanding Myalgia and Myositis
Statin-induced muscle pain affects up to 30% of users, ranging from mild myalgia to severe immune-mediated myositis. Learn the differences, warning signs, and what to do if you're experiencing muscle weakness or pain while on statins.
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FDA Bioequivalence Standards for NTI Drugs: Special Requirements Explained
The FDA applies strict bioequivalence rules to narrow therapeutic index (NTI) drugs like warfarin and phenytoin, requiring tighter limits (90-111%) and lower variability than standard generics to ensure safety and efficacy.
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Oral Corticosteroid Burden in Severe Asthma: Proven Alternatives That Work
Oral corticosteroids help control severe asthma but come with dangerous long-term side effects. Learn about proven alternatives like biologics that reduce steroid dependence, lower hospitalizations, and improve quality of life.
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Allergen Avoidance: Environmental Control and Home Strategies for Better Allergy Relief
Learn science-backed home strategies to reduce allergens like dust mites, pet dander, and mold. Discover how humidity control, HEPA filters, and bedding covers can cut symptoms without drugs.
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Questions to Ask Your Pharmacist About Prescription Medications
Knowing what to ask your pharmacist about prescription medications can prevent dangerous interactions, reduce side effects, and save money. Learn the key questions to ask for safer, smarter medication use.
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OTC to Prescription Switches: Safety Tips for Consumers Using Medications Without a Doctor
OTC switches make medications easier to access, but they also increase risks like drug interactions, misdiagnosis, and overdose. Learn how to use them safely, especially if you're over 65 or on multiple prescriptions.
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How Long Does the FDA Take to Approve Generic Drugs? 2025 Timelines Explained
Discover how long the FDA takes to approve generic drugs in 2025, from standard 10-month reviews to fast-tracked 1-2 month approvals for critical medications. Learn what affects approval time and why it matters for your health.
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Antihistamine Allergies and Cross-Reactivity: What to Watch For
Some people develop allergic reactions to antihistamines instead of relief - a rare but real condition called paradoxical hypersensitivity. Learn why this happens, which drugs are most likely to trigger it, and what to do if your allergy meds make things worse.
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Opioid Therapy: When It’s Appropriate and How to Avoid Dependence
Opioid therapy can help with severe pain but carries serious risks of dependence and overdose. Learn when it's appropriate, how to reduce risks, and what alternatives exist under current medical guidelines.
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Urticaria: Understanding Hives, Common Triggers, and How Antihistamines Work
Urticaria, or hives, are itchy, raised welts caused by histamine release. Learn about common triggers, how antihistamines work, and what to do when they don't help - including new treatments like remibrutinib and omalizumab.
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Bioequivalence of Combination Products: Special Testing Challenges
Bioequivalence testing for combination products like fixed-dose combos and drug-device systems faces unique scientific and regulatory hurdles. Unlike single-drug generics, proving sameness requires complex studies, inconsistent methods, and costly trials-delaying affordable access for patients.
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