Doxycycline Dosage – What You Need to Know

Doxycycline is a common antibiotic used for everything from acne to Lyme disease. Getting the dose right helps it work well and cuts the risk of side effects. Below you’ll find the typical amounts, how often to take them, and a few practical tips that make the whole process easier.

Common Dosing Schedules

Acne: Most doctors start adults on 100 mg once daily. Some prefer 50 mg twice a day to keep blood levels steady. Treatment usually lasts 3‑6 months, but you can stay on it longer if your skin needs it.

Respiratory infections (e.g., pneumonia, bronchitis): The usual adult dose is 100 mg twice daily for 7‑14 days. Children over 8 years old get 2.2 mg per kilogram of body weight, taken twice a day.

Lyme disease: Early disease is treated with 100 mg twice daily for 10‑21 days. For later stages, doctors may extend the course to 28 days or more, still at 100 mg twice daily.

Travel‑related malaria prophylaxis: Start 200 mg (two 100 mg tablets) one day before entering a malaria area, then continue 200 mg daily throughout the stay and for four weeks after leaving.

Sexually transmitted infections (chlamydia, gonorrhea): A single dose of 200 mg works for uncomplicated chlamydia. For gonorrhea, it’s combined with another antibiotic, but the doxycycline part stays at 100 mg twice daily for 7 days.

Remember, these are general guidelines. Your doctor may adjust the dose based on your kidney or liver function, age, or other medicines you’re taking.

Tips for Taking Doxycycline

Take doxycycline with a full glass of water and stay upright for at least 30 minutes. This helps prevent irritation or ulcers in the esophagus.

Avoid dairy products, antacids, calcium, iron, or magnesium supplements within two hours of your dose. Those minerals bind to the drug and lower how much your body absorbs.

If you notice stomach upset, try taking the pill with food. A light snack works for most people, but a heavy, fatty meal can slow absorption.

Sun sensitivity is a real side effect. Wear sunscreen, a hat, and sunglasses if you’re outdoors for a long time, especially during the first two weeks.

Missed a dose? Take it as soon as you remember, unless it’s almost time for the next one. Don’t double‑dose to catch up.

Store doxycycline at room temperature, away from moisture and heat. Keep the bottle tightly closed to protect it from humidity.

Finally, finish the full course even if you feel better early. Stopping too soon can let bacteria survive and become resistant.

With the right dose and a few simple habits, doxycycline can treat a wide range of infections safely and effectively. Always follow your prescriber's instructions and ask questions if anything feels unclear.

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Kevin Richter Sep, 25 2025

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